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Year : 2011  |  Volume : 1  |  Issue : 1  |  Page : 9-14

Toxoplasmosis - An update


Centre for AIDS and Related Diseases, National Center for Disease Control, New Delhi, India

Correspondence Address:
Veena Mittal
Additional Director and Head, Zoonosis Division, National Center for Disease Control, 22 Shamnath Marg, Delhi-110054
India
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Read associated Retraction Notice: Retraction Notice with this article

DOI: 10.4103/2229-5070.72109

PMID: 23508064

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Toxplasmosis is an important zoonotic disease caused by protozoan parasite Toxoplasma gondii. The disease affects one-third of the total world population. Transmission of the disease is mainly by ingestion of food or water contaminated with oocysts. Congenital toxoplasmosis occurs from the transplacental passage of the parasite from mother to fetus. In most adults it does not cause serious illness, but it can cause blindness and mental retardation in congenitally infected children, and it is a devastating disease in immunocompromised individuals. Diagnosis of toxoplasmosis can be established by the direct detection of the parasite or by serological methods. The most commonly used and effective therapeutic regimen is the combination of pyrimethamine with sulfadiazine and folinic acid. This article provides an overview and update on transmission, diagnosis, management, and prevention of toxoplasmosis.


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