|Year : 2019 | Volume
| Issue : 2 | Page : 69-70
Microbial links to noninfectious diseases: The way forward
Subhash Chandra Parija
Vice-Chancellor, Sri Balaji Vidyapeeth (Deemed to be University), Puducherry, India
|Date of Acceptance||28-Aug-2019|
|Date of Web Publication||18-Sep-2019|
Subhash Chandra Parija
Vice-Chancellor, Sri Balaji Vidyapeeth (Deemed to be University), Puducherry
|How to cite this article:|
Parija SC. Microbial links to noninfectious diseases: The way forward. Trop Parasitol 2019;9:69-70
Greetings from the desk of the editor!
Welcome to the second issue of Tropical Parasitology for the year 2019.
As we are moving forward in the 21st century, we are being confronted with myriad manifestations of microbial infections and the strict frontier between communicable and noncommunicable diseases is being breached now and again. The association of viruses and certain parasites with malignancies is well established, and the discovery of Helicobacter pylori in the last century was a great turning point. The new kid in town who is now the talk of the scientific town is the gut microbiome. A flurry of research activities in this new field has established that gut microbiota is an important regulator of host metabolism. The microbial metabolites can influence a plethora of life processes, and any disturbance in the gut microbiome (dysbiosis) can have pathological consequences in the individual. Gut dysbiosis is associated with disruption of the gut homeostasis which can lead to various noncommunicable diseases since microbiota-derived metabolites are either depleted or generated at harmful concentrations. This provides a theoretical framework for linking microorganisms to noncommunicable diseases. A great majority of protozoan and helminth parasites have their residence in the human gut and may produce devastating alterations in the normal commensal flora of the intestine. The changes may be imperceptible in acute infections, but a quantum change in the overall body homeostasis can occur in chronic infections.
A look at the contents of the present issue of Tropical Parasitology will reveal that a wide range of topics have been covered in this edition. Adkoli and Parija have continued their series on systems approach in medical education from the previous issue and have analyzed the systems approach in bridging education, research, and patient care in the present issue. The review article on the possible role of Toxoplasma infection in the genesis of bipolar disorders and schizophrenia and a letter to the editor on the role of intestinal helminth infections in multiple sclerosis reiterate the increasing importance of infections in the multifactorial etiology of certain noncommunicable diseases. Three original articles, primarily on Plasmodium vivax, have discussed its clinical spectrum, cytokine profile, and the genetic diversity.Echinococcus containment has been dealt with in an article from Iran, while cutaneous leishmaniasis infection in India is the subject of another study. Two dispatches, have focused on the histopathological and cytological diagnosis of filariasis and one original article has highlighted the utility of cytology in the diagnosis of parasitological infection. Finally, a report from Indonesia describes the presence of sparganum in frog meat and its antecedent threat to humans. In our regular column on face to face, Dr. Sarman Singh shares his experience in parasitology, in particular on visceral leishmaniasis.
| References|| |
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Adkoli BV, Parija SC. Systems approach in medical education: The thesis, antithesis, and synthesis. Trop Parasitol 2019;9:3-6.
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Adkoli BV, Parija SC. Applying systems approach for bridging education, research, and patient care in a health sciences university. Trop Parasitol 2019;9:77-82. [Full text]
Chaudhury A, Ramana BV. Schizophrenia and bipolar disorders: The Toxoplasma
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Karimi N, Fakhar M, Keighobadi M. The endosymbiotic role of intestinal helminths in multiple sclerosis: Promising probiotic hypothesis. Trop Parasitol 2019;9:131-2. [Full text]
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Sahoo N, Mohanty P, Mohanty S, Naik S. Lymphatic filariasis presenting as a soft tissue swelling in midarm: A histopathological diagnosis at unusual site. Trop Parasitol 2019;9:127-9. [Full text]
Shukla SK, Kusum A, Sharma S, Kandari D. Filariasis presenting as a solitary testicular mass. Trop Parasitol 2019;9:124-6. [Full text]
Pamu PK, Vangala N, Sabbavarapu P, Tandon A. Utility of cytology in the diagnosis of parasitic infestation: A retrospective study. Trop Parasitol 2019;9:93-7. [Full text]
Prasetyo RH, Safitri E. Sparganum in frog meat: A warning for the occurrence of human sparganosis. Trop Parasitol 2019;9:130-1. [Full text]
Face-to-Face: Dr. Sarman Singh. Trop Parasitol 2019;9:133-7.