Year : 2016 | Volume
: 6 | Issue : 1 | Page : 1-
Drug resistance in malaria: A predicament
Subhash Chandra Parija
Director, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India
Subhash Chandra Parija
Director, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry
|How to cite this article:|
Parija SC. Drug resistance in malaria: A predicament.Trop Parasitol 2016;6:1-1
|How to cite this URL:|
Parija SC. Drug resistance in malaria: A predicament. Trop Parasitol [serial online] 2016 [cited 2020 Aug 7 ];6:1-1
Available from: http://www.tropicalparasitology.org/text.asp?2016/6/1/1/175022
The year that was witnessed sharing of the Nobel prize for physiology being shared by Dr. William C. Campbell and Dr. Satoshi Ōmura for their discovery of Ivermectin and Dr. Tu Youyou for her discovery of the wonder drug artemisinin. These antiparasitic drugs have drastically reduced the incidence of river blindness and lymphatic filariasis, as well as have shown efficacy against a large number of parasites and have significantly reduced the mortality rates for malaria, respectively. This edition salutes these heroes and brings to the fore that nature has many more solutions available, and we only need to tap them.
Leishmaniasis continues to scourge the Indian subcontinent, and it is considered as a disease complex rather than a single disease entity and is among the least studied and most neglected of tropical diseases. The guest commentary focuses on the path toward its elimination from the Indian subcontinent.
The current issue focuses on the artemisinin-based combination therapies that are now recommended by WHO as the first-line treatment for falciparum malaria. The existing chloroquine resistance in Plasmodium falciparum is compounded by the recent emergence of artemisinin resistance. There are numerous molecular markers that have been implicated in the chloroquine and artemisinin resistance.
The systematic review on Endolimax nana explores this lesser studied ameba in terms of its morphology, taxonomy, genetic diversity, host specificity, and epidemiology. The clinical significance of this parasite is still unknown, though its importance as an endosymbiont is better accepted.
The "Ethics in series" focuses on the two schools of thought that exist in ethics regarding decision-making: Deontological and utilitarian. It sheds light on both the aspects of ethics and their shortcomings and that a balance between these two perspectives is required to bring in better harmony and justice to medical practice.
The section on "Face-to-face" presents an interview with Prof. S. Kawazu regarding tick-borne diseases particularly focusing on babesiosis. He is an expert in this field and has shared his experience and thoughts on the same.
The issue reviews a recent addition to the list of best textbooks available in parasitology in the "Book review" titled "Parasitology: A Conceptual Approach." This book authored by Eric S. Loker and Bruce V. Hofkin introduces one to high standards of perception in conceptualizing newer concepts and principles of parasitology without bypassing key elements of a conventional parasitology. One must agree that the authors have an extensive teaching and research experience in various aspects of the parasitology and have offered their rich expertise to each chapter in this marvel.