Home Print this page Email this page Small font sizeDefault font sizeIncrease font size
Users Online: 537
Home | About us | Editorial board | Search | Ahead of print | Current issue | Archives | Submit article | Instructions | Subscribe | Contacts | Login 
     
ORIGINAL ARTICLE
Year : 2012  |  Volume : 2  |  Issue : 2  |  Page : 116-118

Comparative study of double blind clinical trial in side-effects among Areca catechu l., Thai traditional herbal formula and mebendazole


1 Department of Biotechnology, Mahasarakham University, Mahasarakham, Thailand
2 Faculty of Technology, Mahasarakham University, Mahasarakham, Thailand
3 Faculty of Public Health, Mahasarakham University, Mahasarakham, Thailand

Correspondence Address:
Buavaroon Srichaikul
Faculty of Public Health, Mahasarakham University, Kantharawichai, Mahasarakham, 44150
Thailand
Login to access the Email id


DOI: 10.4103/2229-5070.105176

PMID: 23767018

Rights and Permissions

Background: This study was carried out in Mahasarakham Primary Healthcare Center, Mahasarakham province in the area of Northeastern of Thailand. The experiment was randomized control trial clinical study in order to examine the side effects of Areca catechu Linn., Thai traditional formulae medicine, mebendazole in the treatment of anti-helmintic activity of mixed worms infection in human. Materials and Methods: The experimental group consisted of 15 patients and 5 patients for control group with inclusion and exclusion criteria, which were screened by parasitologist with the selection of mixed worm infection patient samples. The investigation of side effects was recorded after the treatment of each group of patient with different kinds of 4 group of medicine. Results: The percentage of side effects was collected by nurses and confirmed by the physician at Mahasarakham Health Center, which were diarrhea and nausea side effects. The percentage of side effects by the treatments of Areca catechu Linn., Thai traditional formulae medicine, mebendazole were investigated by the physician and the pharmacist, which the result showed 20% of diarrhea in Areca catechu Linn., 20% of nausea in Areca catechu Linn, 20% in side effect of diarrhea in mebendazole treatment, and no side effects were found by the treatment of TTFM. The result showed that Areca catechu Linn. had higher side effects among the 3 anti-helmintic drugs. Conclusion: The findings indicate to increase the numbers of samples of worm-infected patients, which the samples can be identified with the specification of helminthes genus and species in order to obtain the efficacy by the treatment using Areca catechu Linn and also indicates to increase various forms of dosage preparations and various demographic locations in Thailand.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed2725    
    Printed140    
    Emailed0    
    PDF Downloaded136    
    Comments [Add]    
    Cited by others 2    

Recommend this journal