Tropical Parasitology

PRESIDENTIAL ORATION
Year
: 2021  |  Volume : 11  |  Issue : 1  |  Page : 3--10

Molecular diagnosis of infectious parasites in the post-COVID-19 era


Subhash Chandra Parija1, Abhijit Poddar2 
1 Vice Chancellor, Sri Balaji Vidyapeeth University, Puducherry, India
2 Scientist, Sri Balaji Vidyapeeth University, Puducherry, India

Correspondence Address:
Subhash Chandra Parija
Sri Balaji Vidyapeeth University, Puducherry
India

The endemicity of several parasitic diseases across the globe and recent evidence of distress among COVID-19 patients with preexisting parasitic infections requires strengthening One Health framework and advanced strategies for parasitic detection. Owing to the greater sensitivity and accuracy, molecular technologies such as conventional polymerase chain reaction (PCR), reverse transcription (RT)-PCR, nested PCR, loop-mediated isothermal amplification (LAMP), and xMAP technology have been extensively studied for parasitic diagnosis. Varieties of genes have been targeted for primer development where 18S rRNA, internal transcribed spacer regions, and mitochondrial DNAs coding for cytochrome, and other enzymes have been widely used. More recent, low-cost sequencing and advances in big data management have resulted in a slow but steady rise of next-generation sequencing-based approaches for parasite diagnosis. However, except for few parasites of global concerns such as Plasmodium and Entamoeba, most of the molecular tools and technologies are yet to witness bench to bedside and field translations. This review looks into some of the advancements in the molecular diagnosis of parasites that have potential relevance to clinical purposes and may pave the way toward disease management in an efficient and timely manner.


How to cite this article:
Parija SC, Poddar A. Molecular diagnosis of infectious parasites in the post-COVID-19 era.Trop Parasitol 2021;11:3-10


How to cite this URL:
Parija SC, Poddar A. Molecular diagnosis of infectious parasites in the post-COVID-19 era. Trop Parasitol [serial online] 2021 [cited 2021 Jun 18 ];11:3-10
Available from: https://www.tropicalparasitology.org/article.asp?issn=2229-5070;year=2021;volume=11;issue=1;spage=3;epage=10;aulast=Parija;type=0